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Exploding nanobubbles can kill cancer cells By Robert F. ServiceFeb. 15, 2016

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Exploding nanobubbles can kill cancer cells

By Robert F. ServiceFeb. 15, 2016 , 11:00 AM

Clusters of gold atoms can detect and kill cancer cells commonly left behind after tumor-removal surgery, according to a study of a new nanotechnology technique. For now, the approach has only been tried in a handful of mice. But the researchers are designing a clinical trial that could begin testing the therapy in humans in the next 2 years. If the technique proves successful in people, it could dramatically improve the odds for cancer patients, particularly in cases where surgically removing an entire tumor is impossible.

When surgeons operate on cancer patients, they do their best to remove every last diseased cell, because any left behind can grow into new tumors or metastasize throughout the body. Oncologists then typically follow up surgery with either radiation treatments or chemotherapy to increase the chances of eliminating any residual tumor cells. But this standard approach to fighting cancer is anything but foolproof.

In recent years, physicians and scientists have looked to nanotechnology for help. One approach pioneered over the last decade by researchers at Rice University in Houston, Texas, and elsewhere has shown that clusters of gold atoms known as nanoparticles can serve as a potent weapon against cancer cells. Solid cancer tumors typically have leaky blood vessels. As a result, when gold nanoparticles are injected into the bloodstream, they tend to seep out of the vessel openings and congregate around tumors. To clean up their surroundings, those cells then often engulf the nanoparticles. But once inside the cells, the nanoparticles can act as Trojan horses. When researchers hit the gold atoms with infrared laser light, which can travel through centimeters of tissue, the particles heat up and kill the cancer cells.

Unfortunately, the nanoparticle heater strategy has two problems, says Dmitri Lapotko, a physicist formerly with Rice and now head of laser science at Masimo Corporation, a medical nanotechnology company in Irvine, California. The first is that some gold nanoparticles invariably end up in and around normal cells, so healthy tissue can get damaged when the lasers go after cancers. As well, the lasers that are normally used for heating the particles fire continuous beams of infrared light. This too spreads the heat far beyond cancer cells and into the normal tissue. In cases where tumors grow in and around vital tissues, such as nerves or arterial walls, any collateral damage to healthy tissues can be debilitating or dangerous.

In an effort to narrow the therapy’s focus, Lapotko and colleagues sought to modify the approach to zapping nanoparticles. They started with mice that had been implanted with human squamous cell carcinoma, cancer cells common in human head and neck tumors that are particularly difficult to treat with standard therapies. They decorated their gold nanoparticles with immune protein antibodies, which specifically latch onto receptors that sit on the surface of squamous cells. That concentrated the particles, creating clusters of dozens of them in and around cancer cells. And instead of firing continuous laser beams, the researchers fired only ultrashort infrared pulses.

As hoped, this prevented the heat from spreading to surrounding normal tissues. But the approach had an even more important effect: It caused temperatures to rise higher where there were large clusters of gold nanoparticles. This vaporized adjacent water molecules, creating tiny bubbles that quickly expand and burst, ripping apart the cancer cells. They key, Lapotko says, is that “nanoparticle clusters produce nanobubbles in cancer cells and not normal tissue.”

Online today inNature Nanotechnology, Lapotko and his colleagues report that those mini-explosions made it possible not only to pick up sound from where tumor cells were located—and thereby detect the presence of as few as three cancer cells—but it also destroyed the cells in the process. For cases in which it was possible to surgically resect most of the cancer tissue, 100% of the animals survived, thanks to the fact that no residual cancer cells remained alive. And in cases where only partial surgical removal of a tumor was an option, the survival rate for the animals doubled.

“This is very, very interesting,” says Mien-Chie Hung of the University of Texas MD Anderson Cancer Center in Houston, who is exploring treating tumors with nanoparticles. Hung notes that the approach dovetails very well with conventional surgery that is able to remove large tumors but is unable to identify cancer cells that remain behind. The new technique, he says, acts like microscopic surgery to target those residual cells. Hung emphasizes that many oncology approaches that work in animals never wind up as effective in humans. But if this one does, it could open a whole new window into spotting and eliminating residual cancer cells left behind after surgery.

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DOI: 10.1126/science.aaf4067


Re-enchanting The Earth - Bruce Lyon -

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Re-enchanting The Earth

In the ancient world the land was seen as alive and enchanted in the deep sense of that word. To chant into and with the land was part of the practise of prayer, worship and reverence for this living being we form part of. In NZ the Maori carried greenstone over the land and retold the ancient stories. In Australia the aborigines sang as they walked along the song lines. In Ireland the nature spirits were part of everyday reality. In Greece every glade, every stream and every hill was enchanted and home to one or other god or goddess. Gradually as the development of the mind and ideas, particularly monotheism, became dominant, we stopped listening to the chants of the land itself and started imposing on it instead as if it was a blank canvas for our ideologies.

As different civilisations and religions rose and fell they built temples on top of each other competing for the supremacy of their god, their culture, their worldview and their dominion. Today the modern western world has come to the point where land is often just treated as an asset, something that can be owned, traded, 'developed' and defended. This is quite funny when we really stop to examine it. It is as if one of the millions of mites that lived on my skin erected a little mite flag on my elbow or nipple and proclaimed ownership in perpetuity. A creature that lives for less than a hundred years claims ownership of something that has been alive for 5 billion. Modern society is based on 'property rights' and competition. No doubt this is all part of some larger evolution but the consequences for our own bodies has been dire. The mentality that treats land as a thing to be owned also gets applied to our own sacred land, the temple of our body. It becomes 'our' body to do what we want with. The ego holds dominion.

The result as we all know is reflected in the state of our health, our oceans, our forests, and our feelings. Over the last few decades a gradual wave has been building to re-turn to a listening to the chants of the land and our bodies. Our consciousness has become aware of the impoverishment, depression and suffering that results from the egoic stance. Gradually one by one we come to our knees before the body again to ask forgiveness, seek atonement and start to listen instead of imposing our will. We come to the land and our bodies as a lover. We let go of possession and allow ourselves to be supported. Life returns, the radiance of the goddess is wooed back into the streams and forests ; back into the landscapes of the body, the armpits start to sing, the hands shed tiny droplets of light as they dance on the computer keys or stroke a lover's face. The wild powers of nature that have been driven back into the last remaining patches of wilderness begin to reemerge.

In the body this wildness has had to retreat into the genitals, the last temples that have kept the sacred fire alive albeit in an often distorted and barely recognisable way. The life force of our sexuality has refused to be owned by the ego and keeps itself alive in a hundred secret ways. When we turn with humility towards these powers they too begin to reemerge and eros starts to flow out of these mysterious sanctuaries and bring vitality , pleasure and beauty back to the whole embodied being. We come to ground. We are enchanted. The mystery of surrender to the earth is that it is this very act which restores the sacred relationship. The ego tries to move away from the earth to transcend its own mortality, but deep acceptance of our physical reality brings our awareness and attention back to earth. That attention when it has been awakened and enlightened, IS love. When we shine that love upon our own bodies and the body of the planet then one by one the secret portals open, the ancient dragons of the earth appear and the magic returns. The goddess awakens ( in our awareness that is ) and our world becomes re-enchanted. The heaven we went looking for is revealed as being here all the time, the veils fall from our eyes and we experience the original innocence and delight of this earthly paradise.


REICHI - Ganoderma e l’avanzamento d’età

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Ganoderma IT Ganoderma e l’avanzamento d’età

26 settembre 2012 | Autore Redazione

Il Ganoderma Lucidum è un valido rimedio e un potente antiossidante per la vecchiaia e per tutti i componenti che fanno parte e favoriscono la vecchiaia!
Il Ganoderma Lucidum contiene i polisaccaridi, in grado di eliminare il radicale ossidrile, di anti-ossidazione, anti-invecchiamento efficacia; triterpenoidi.
Finora nel Ganoderma Lucidum sono stati trovati più di 150 tipi di composti che possono essere suddivisi in dieci categorie: polisaccaridi, triterpeni, nucleosidi, peptidi, amminoacidi, alcaloidi, steroidi, alcoli grassi e oli, furano, ioni inorganici, organici germanio.

Molti studi medici e grandi ricercatori dichiarano che il Ganoderma Lucidum non è un farmaco ne un additivo alimentare, esso consente ai produttori di pubblicare più le istruzioni complete per l’uso che in precedenza ha permesso di includere avvertenze, le controindicazioni e gli effetti collaterali.

Gano Ganoderma

Ci sono alcune dichiarazioni importanti sono state inseriteb dall’International Ganoderma Research Institute di New York nel 1993 al fine di promuovere la ricerca scientifica Internazionale e medicinali.
La ricerca sul Ganoderma negli Stati Uniti non è molto estesa, la ragione principale è la mancanza di fondi per la ricerca, l’interesse del pubblico in erboristeria è in crescita, le vendite di prodotti a base di erbe è in aumento ogni anno, con scarso effetto sul finanziamento della ricerca.

L’importante è mantenere sempre la mente sveglia facendo diversi esercizi e averla sempre attiva, oltre a farti ottenere una mente sveglia, riesce a non farti invecchiare e ad ottenere la longevità, quindi il tuo corpo risulterà più sano a vista.
Il Ganoderma Lucidum è valido anche per molti altri tipi di patologie come le allergie, l’asma, problemi cardiovascolari e respiratori, infezioni, artrite, trombosi e molte altre malattie.
Il Ganoderma Lucidum è il più potente antiossidante che esiste al mondo inoltre è un adattogeno ciò significa che aiuta il nostro corpo a diverse sollecitazioni come la temperatura, sbalzi d’umore e stress, inoltre il Ganoderma è un Nutraceutico e quindi ha tutte le basi per essere un medicinale ma senza l’effetto dei medicinali.
Il Ganoderma è in grado di eliminare i materiali di tossine nel sangue, rafforzare il cuore e promuovere la circolazione del sangue coronarico, il germanio organico è stato chiamato come il “più pulito nel vaso sanguigno” per la funzione speciale di contribuire ad eliminare le tossine nel sangue.
Il Ganoderma Lucidum aumenta la capacità antiossidante del plasma e valorizza le risposte immunitarie, viene usato per molti tipi di fattori che disturbano il nostro corpo e soprattutto il nostro sistema immunitario


A lungo andare...Snoopy

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Le più belle foto d'ambiente del 2013

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